The site itself is safe, but some of the download links do have viruses and the "fast download" links are ads, and they are the kind that really mess up your computer.
Symantec's products are very effective and they get stuff done. They're also safe to use!
Before Symantec acquired Pctools, Pctools acted like adware, especially the registry mechanic. However, now that Symantec is in charge of Pctools, the products are safe, simple, and effective. I personally use pctools' products and they get stuff done!
McAfee detected a trojan known as "Js/exploit.gen"
in the file mediafire_com .htm
As a google chrome user, I've had no issues with this site. But I can't really say the same thing about Internet Explorer.